Science Biology Evolution Reptile'pee crystals' might help treat kidney stones and gout Researchers studied urate solids from over 20 snake and lizard species. Breakthroughs, discoveries, and DIY tips sent every weekday. It may come as a surprise, but not all animals pee . While almost every living organism possesses an excretory system, most reptiles don't eliminate excess nitrogen-containing waste in the form of liquid urine . Instead, they rid themselves of the chemicals by expelling them in the form of crystalline solids called urates.

Determining the type of kidney stones is crucial for prescribing appropriate treatments to prevent recurrence. Currently, various approaches exist to identify the type of kidney stones. However, obtaining results through the reference ex vivo identification procedure can take several weeks, while in vivo visual recognition requires highly trained specialists. For this reason, deep learning models have been developed to provide urologists with an automated classification of kidney stones during ureteroscopies. Nevertheless, a common issue with these models is the lack of training data. This contribution presents a deep learning method based on few-shot learning, aimed at producing sufficiently discriminative features for identifying kidney stone types in endoscopic images, even with a very limited number of samples. This approach was specifically designed for scenarios where endoscopic images are scarce or where uncommon classes are present, enabling classification even with a limited training dataset. The results demonstrate that Prototypical Networks, using up to 25% of the training data, can achieve performance equal to or better than traditional deep learning models trained with the complete dataset.

Medical image classification is a vital research area that utilizes advanced computational techniques to improve disease diagnosis and treatment planning. Deep learning models, especially Convolutional Neural Networks (CNNs), have transformed this field by providing automated and precise analysis of complex medical images. This study introduces a hybrid deep learning model that integrates a pre-trained ResNet101 with a custom CNN to classify kidney CT images into four categories: normal, stone, cyst, and tumor. The proposed model leverages feature fusion to enhance classification accuracy, achieving 99.73% training accuracy and 100% testing accuracy. Using a dataset of 12,446 CT images and advanced feature mapping techniques, the hybrid CNN model outperforms standalone ResNet101. This architecture delivers a robust and efficient solution for automated kidney disease diagnosis, providing improved precision, recall, and reduced testing time, making it highly suitable for clinical applications.

Determining the type of kidney stones allows urologists to prescribe a treatment to avoid recurrence of renal lithiasis. An automated in-vivo image-based classification method would be an important step towards an immediate identification of the kidney stone type required as a first phase of the diagnosis. In the literature it was shown on ex-vivo data (i.e., in very controlled scene and image acquisition conditions) that an automated kidney stone classification is indeed feasible. This pilot study compares the kidney stone recognition performances of six shallow machine learning methods and three deep-learning architectures which were tested with in-vivo images of the four most frequent urinary calculi types acquired with an endoscope during standard ureteroscopies. This contribution details the database construction and the design of the tested kidney stones classifiers. Even if the best results were obtained by the Inception v3 architecture (weighted precision, recall and F1-score of 0.97, 0.98 and 0.97, respectively), it is also shown that choosing an appropriate colour space and texture features allows a shallow machine learning method to approach closely the performances of the most promising deep-learning methods (the XGBoost classifier led to weighted precision, recall and F1-score values of 0.96). This paper is the first one that explores the most discriminant features to be extracted from images acquired during ureteroscopies.

This contribution presents a deep-learning method for extracting and fusing image information acquired from different viewpoints, with the aim to produce more discriminant object features for the identification of the type of kidney stones seen in endoscopic images. The model was further improved with a two-step transfer learning approach and by attention blocks to refine the learned feature maps. Deep feature fusion strategies improved the results of single view extraction backbone models by more than 6% in terms of accuracy of the kidney stones classification.

Abstract--This contribution presents a deep learning method for the extraction and fusion of information relating to kidney stone fragments acquired from different viewpoints of the endoscope. Surface and section fragment images are jointly used during the training of the classifier to improve the discrimination power of the features by adding attention layers at the end of each convolutional block. This approach is specifically designed to mimic the morpho-constitutional analysis performed in ex-vivo by biologists to visually identify kidney stones by inspecting both views. The addition of attention mechanisms to the backbone improved the results of single view extraction backbones by 4% on average. Moreover, in comparison to the state-of-the-art, the fusion of the deep features improved the overall results up to 11% in terms of kidney stone classification accuracy.

Knowing the cause of kidney stone formation is crucial to establish treatments that prevent recurrence. There are currently different approaches for determining the kidney stone type. However, the reference ex-vivo identification procedure can take up to several weeks, while an in-vivo visual recognition requires highly trained specialists. Machine learning models have been developed to provide urologists with an automated classification of kidney stones during an ureteroscopy; however, there is a general lack in terms of quality of the training data and methods. In this work, a two-step transfer learning approach is used to train the kidney stone classifier. The proposed approach transfers knowledge learned on a set of images of kidney stones acquired with a CCD camera (ex-vivo dataset) to a final model that classifies images from endoscopic images (ex-vivo dataset). The results show that learning features from different domains with similar information helps to improve the performance of a model that performs classification in real conditions (for instance, uncontrolled lighting conditions and blur). Finally, in comparison to models that are trained from scratch or by initializing ImageNet weights, the obtained results suggest that the two-step approach extracts features improving the identification of kidney stones in endoscopic images.

The collection and the analysis of kidney stone morphological criteria are essential for an aetiological diagnosis of stone disease. However, in-situ LASER-based fragmentation of urinary stones, which is now the most established chirurgical intervention, may destroy the morphology of the targeted stone. In the current study, we assess the performance and added value of processing complete digital endoscopic video sequences for the automatic recognition of stone morphological features during a standard-of-care intra-operative session. To this end, a computer-aided video classifier was developed to predict in-situ the morphology of stone using an intra-operative digital endoscopic video acquired in a clinical setting. The proposed technique was evaluated on pure (i.e. include one morphology) and mixed (i.e. include at least two morphologies) stones involving "Ia/Calcium Oxalate Monohydrate (COM)", "IIb/ Calcium Oxalate Dihydrate (COD)" and "IIIb/Uric Acid (UA)" morphologies. 71 digital endoscopic videos (50 exhibited only one morphological type and 21 displayed two) were analyzed using the proposed video classifier (56840 frames processed in total). Using the proposed approach, diagnostic performances (averaged over both pure and mixed stone types) were as follows: balanced accuracy=88%, sensitivity=80%, specificity=95%, precision=78% and F1-score=78%. The obtained results demonstrate that AI applied on digital endoscopic video sequences is a promising tool for collecting morphological information during the time-course of the stone fragmentation process without resorting to any human intervention for stone delineation or selection of good quality steady frames. To this end, irrelevant image information must be removed from the prediction process at both frame and pixel levels, which is now feasible thanks to the use of AI-dedicated networks.

Doctors use several types of imaging to detect kidney stones including high resolution CT scans and kidney-ureter-bladder x-ray. Doctors analyze the images to assess the stone's size, shape, and position to choose the best treatment to remove the stones. Once the stone is removed, it is examined to determine what type of stone it is. Doctors also test the patient's blood and urine for calcium, phosphorus, and uric acid to determine what caused the stone to form. Doctors use this information to help patients reduce the risk of developing kidney stones in the future.

Whether or not you're aware, your Google searches, questions posed to Siri, and Facebook timeline all rely on artificial intelligence (AI) to perform effectively. Artificial intelligence is the simulation of human intelligence processes by machines. The goal of artificial intelligence is to build models that can perform specific tasks as intelligently as humans can, if not better. Much of the AI you encounter on a daily basis uses a technique known as machine learning, which uses predictive modeling to generate accurate predictions when given random quantities of data. Because predictive models are built to find relational patterns in data, they learn to favor efficiency over fairness.